Profile
Abstract
Martina Protschka is a biologist and works since 2004 at the University of Leipzig. Under supervision of Prof. Manfred Blessing she investigated the Ets-transcription factor Elf3 in the murine gut at the Institute of Molecular Pathogenesis. Since 2010 she works for Prof. Gottfried Alber at the Institute of Immunology at the faculty of Veterinary Medicine.
Her methodological portfolio includes molecular genetic methods, amongst others establishment and realization of gene expression analysis by means of RT-qPCR, execution and improvement of immunhistological detection procedures, protein biochemistry (western blotting), establishment of primary cell cultures (muscles, fibroblasts, keratinocytes), cultivation, proliferation and cryoconservation of eukaryotic cells, virus production and titer determination as well as infection of eukaryotic cells using virus.
Professional career
- since 07/2004
Postgraduate at the Center for Biotechnology and Biomedicine at the Universität Leipzig, Germany - 10/1994 - 06/2004
Postgraduate at the I. Med. Department, Faculty of Medicine at Johannes Gutenberg-University in Mainz, Germany: construction of eukaryotic expression vectors, generation and analysis of transgenic mice, analysis of expression on RNA- /protein level - 05/1992 - 10/1993
Postgraduate in preclinical research at the Sandoz AG, Basel, Switzerland: development and optimization of different ELISAs, analytical and preparative affinity chromatography, cell culture - 01/2004 - 07/2009
Promotion in the field of Biology at the Johannes Gutenberg-University Mainz, Germany
Education
- 03/1991 - 10/1991
Diploma thesis at the Alfred Wegener Institute for Polar and Marine Research, Bremerhaven, Germany: investigation on occurrence and activity of extra cellular enzymes of fungi like marine protists - 10/1986 - 01/1992
Biotechnology studies at the University of applied sciences Weihenstephan, Germany
- show detailsHeyen, L.; Müller, U.; Siegemund, S.; Schulze-Richter, B.; Protschka, M.; Alber, G.; Piehler, D.Lung epithelium is the major source of IL-33 and is regulated by IL-33-dependent and IL-33-independent mechanisms in pulmonary cryptococcosisPathogens And Disease. 2016. 74 (7).
- show detailsSchulze-Richter, B.; Piehler, D.; Eschke, M.; Heyen, L.; Protschka, M.; Köhler, G.; Alber, G.Therapeutic expansion of CD4(+)FoxP3(+) regulatory T cells limits allergic airway inflammation during pulmonary fungal infectionPathogens and disease. 2016. 74 (4).
- show detailsPiehler, D.; Eschke, M.; Schulze-Richter, B.; Protschka, M.; Müller, U.; Grahnert, A.; Richter, T.; Heyen, L.; Köhler, G.; Brombacher, F.; Alber, G.The IL-33 receptor (ST2) regulates early IL-13 production in fungus-induced allergic airway inflammationMucosal Immunology. 2016. 9 (4). pp. 937–949.DOI: 10.1038/mi.2015.106
- show detailsMüller, U.; Stenzel, W.; Piehler, D.; Grahnert, A.; Protschka, M.; Köhler, G.; Frey, O.; Held, J.; Richter, T.; Eschke, M.; Kamradt, T.; Brombacher, F.; Alber, G.The role of macrophages in IL-4 receptor (IL-4R)-dependent pathology in pulmonary cryptococcosisMYCOSES. 2015. 58 (S3). pp. 65–66.DOI: 10.1111/myc.12362
- show detailsPiehler, D.; Eschke, M.; Schulze-Richter, B.; Protschka, M.; Müller, U.; Grahnert, A.; Richter, T.; Heyen, L.; Köhler, G.; Brombacher, F.; Alber, G.The IL-33 receptor (ST2) regulates early IL-13 production in fungus-induced allergic airway inflammationMycoses. 2015. 58 (S3). pp. 4–4.DOI: 10.1111/myc.12361